A rare mitochondrial disease is shown in this pedigree. I 2 II 2 3 4 III 1 2 3 Erza, individual II-3, is affected. So are all her three children. However, Erza's mother Hinata does not show any of the symptoms of this mitochondrial disease. What are two possible explanations for this?

Answers

Answer 1

Hinata may have the disease-causing mitochondrial DNA but not show symptoms or Erza may have acquired the disease-causing mitochondrial DNA from her father.

The fact that Erza's mother Hinata does not show any symptoms of the mitochondrial disease while her daughter and grandchildren do suggests that the disease is maternally inherited.

This is because mitochondria, which contain their own DNA, are typically passed down from the mother to her offspring.

One possible explanation for Hinata's lack of symptoms could be that she is a carrier of the disease-causing mutation but does not show symptoms due to a phenomenon called heteroplasmy.

Heteroplasmy refers to the presence of a mixture of normal and mutant mitochondrial DNA in a single cell. If Hinata's cells have a low proportion of the mutated mitochondrial DNA, then she may not show any symptoms.

However, Erza may have a higher proportion of mutated mitochondrial DNA, which could explain why she and her children show symptoms of the disease.

Another possible explanation is that the mutation arose spontaneously in Erza's mitochondrial DNA rather than being inherited from Hinata.

This is known as a de novo mutation and can occur during the formation of the egg cell or early in embryonic development. In this scenario, Hinata would not have the mutation because it did not exist in her mitochondrial DNA.

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Answer 2

Two possible explanations for Erza's mother Hinata not showing any symptoms of the mitochondrial disease, despite her daughter and grandchildren being affected, are:

Maternal inheritance: Mitochondrial DNA (mtDNA) is inherited exclusively from the mother. Therefore, if a mother carries a disease-causing mutation in her mtDNA, all of her children will inherit it. However, since the mutation is only present in the mother's mtDNA, her own symptoms may be absent or mild. This is because the disease-causing mtDNA mutation may not affect all cells equally or may only cause symptoms when present at high levels.

Heteroplasmy: Mitochondria can have multiple copies of mtDNA, and it is possible for an individual to have a mixture of both normal and mutated mtDNA in their cells. This is known as heteroplasmy. If Hinata is heteroplasmic for the disease-causing mtDNA mutation, she may have a low level of mutated mtDNA in her cells, which is not enough to cause symptoms. However, when the mutation is passed on to her offspring, the level of mutated mtDNA may increase, leading to symptoms in her children and grandchildren.

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A technologist performed a STAT spinal fluid count by pipetting undiluted spinal fluid in a Neubauer Counting Chamber and counting both sides of the chamber (4 large WBC squares on each side). A total of 54 White Cells were counted. How many White Cells would there be per cubic millimeter

Answers

The number of white cells is mathematically given as

Avg = 67.5 mm^3

What are White Cells in per cubic millimeter?

Generally, the equation for Avg  is   mathematically given as

Avg =WBC/µL

Where, the addition of  the number of squares

x=(4+4)

x= 8

Therefore

Avg =54/ 8x 0.1 uL

Avg = 67.5

In conclusion, the number of white cells White Cells

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The correct definition for BCC is (b) a cancerous tumor of basal skin cells.

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Answers

Answer:

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Answers

A daughter cell that matures to the inside of the vascular cambium becomes secondary xylem and a daughter cell that matures to the outside of the vascular cambium becomes secondary phloem.

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A daughter cell that matures to the inside of the vascular cambium becomes secondary xylem and a daughter cell that matures to the outside of the vascular cambium becomes secondary phloem.

What vascular cambium is?

The primary meristem in the stem is the vascular cambium, which produces undifferentiated wood cells on the inside and bark cells on the outside. When the vascular cambium is most active, its thickness ranges from around six cells during periods of dormancy to about 14 cells.

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In the roman soldier model for refraction, the soldiers have to stay in line or else they will be
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Answer: A is the answer

The roots of many clover plants produce structures that are filled with bacteria. The clover plants provide food and shelter for bacteria, while the bacteria produce a nutrient that is used by plants. As a result, clover plants that have these structures on their roots grow at a faster rate and are healthier than clover plants that do not have structures.What type of relationship exists between the clover plants that have these structures on their roots and the bacteria in the structure?

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The type of relationship that occurs between the clover plants and the bacterias is called mutualism.

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The limbic system and reticular formation are located ______.

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The limbic system and reticular formation are located throughout two (2) or more areas of the brain.

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When the number of enzymes needed to break down a drug in the liver increases, it is called:_______

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When the number of enzymes needed to break down a drug in the live increases , its is called as Cytochrome P-450 enzymes. It is a group of enzymes that helps in to breakdown to drug via primary mechanism for metabolizing .

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Answers

According to grime, the S strategy is followed by stress-tolerant species.

For plants especially, Grime created a life-history model. Grime categorized factors that restrict plant biomass or productivity in this model in the ways shown as follows. Any condition is known as stress limits plant growth. Examples include a lack of nutrients, water, light, or a low temperature. A disturbance is the partial or complete loss of plant biomass brought on by herbivores, pathogens, or human activity, as well as by environmental variables such as wind, frost, desiccation, soil erosion, or fire. The propensity of nearby plants to share the same amount of space, water molecule, ion of mineral nutrient, or quantum of light is known as competition. Numerous studies have demonstrated that while competitiveness is significant under productive conditions, its significance diminishes as productivity increases.

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What structure is found in all cells that encloses the cell to form the outside?


A. Eukaryotic cells are simpler than prokaryotic cells.


B. Prokaryotic cells are larger than eukaryotic cells.


C. Prokaryotic cells lack membrane-bound organelles, and eukaryotic cells contain membrane-bound organelles.

Answers

Answer: I think its c?

Explanation:

Use the numbers 1,2,3,4 and 5 to place the protein creation steps below in the correct order.

Answers

Answer:

Explanation:

1) Activation of the Amino Acids

2) Transfer of the Amino Acids to tRNA

3) Initiation of polypeptide chain

4) Chain Termination

5) Protein Translocation

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The proper method for cleansing the evacuation port of a wound drainage system is wiping it with an alcohol sponge and is denoted as option D.

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This is a system which is designed to ensure the wound is in the best condition for regeneration and healing such as removal of foreign materials or making it moist.

Alcohol helps to sterilize the affected area and makes it moist thereby making it the most appropriate  choice.

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The options are:

A. Cleanse it with normal saline.

B. Wash it with soap and warm water.

C. Rinse it with sterile water.

D. Wipe it with an alcohol sponge.

How does sweating during exercise help maintain homeostasis?
A.It regulates water concentration in the cells.
B.It regulates body temperature.
C.It regulates ion concentrations in the cells.
D.It regulates transport between cells.

Answers

The correct option is B. It regulates body temperature.

What is homeostasis?

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This is the requirement of optimal functioning for the organism and contains many variables, such as body temperature and fluid balance, being kept within certain pre-set limitations (homeostatic range). Other variables include the pH of extracellular fluid, the engagements of sodium, potassium, and calcium ions, as competently as the blood sugar level, and these need to be regulated despite changes in the atmosphere, diet, or level of activity. Each of these variables is controlled by one or better controllers or homeostatic mechanisms, which together maintain life.Homeostasis exist obtained about by a natural resistance to switch when already in the optimal conditions, and balance is maintained by many regulatory mechanisms. All homeostatic control mechanisms include at least three interdependent elements for the variable being regulated: a receptor, a control center, and an effector.

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EdgeProps: A Computational Platform for Correlative Analysis of Cell Dynamics and Near-Edge Protein Activity

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Developing molecular tools to visualize and control Rho GTPase signaling in living cells has been instrumental in elucidating the mechanisms of cytoskeletal reorganization and causal relationships between activation events in cell function.

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The EdgeProps is a collection of MATLAB scripts divided into three folders corresponding to the three modules of the pipeline.

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What evidence suggests that proteins are synthesized and modified in the rough er as opposed to the smooth er?

Answers

The presence of ribosomes on the rough ER suggests that the proteins are synthesized as well as modified there as opposed to the smooth ER.

Ribosomes are responsible for the synthesis of proteins from the amino acids. They translate each codon on the RNA template and match it with the appropriate amino acid to make a protein. This process is known as translation. Ribosomes can be found free in the cytosol or attached to the surface of the endoplasmic reticulum. When the ribosomes are bound to it, it is known as the rough ER and without it, it is called smooth ER. Smooth ER performs different functions like the synthesis of lipids and phospholipids. Since it does not have ribosomes, it cannot synthesize proteins.

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How do plants maintain homeostasis? Select all that apply.

By exchanging gas through stigmas.
By exchanging gas through stomata.
By closing stomata to prevent water loss.
By altering the activity within a cell with chemical transmitters.
By growing towards sunlight.

Answers

Plants maintain homeostasis by exchanging gas through their stomata (option B). Details about homeostasis can be found below.

What is homeostasis?

Homeostasis is the ability of a system or living organism to adjust its internal environment to maintain a constant state.

Plants maintain homeostasis in their cell by opening a pore called stomata for gaseous exchange to occur i.e. loss of oxygen, intake of carbon dioxide

Therefore, plants maintain homeostasis by exchanging gas through their stomata.

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Provide four major drawbacks to using fossil fuels, such as coal and natural gas, in alberta thermal power stations.

Answers

The four major drawbacks to using fossil fuels, such as coal and natural gas, in alberta thermal power stations is climate change, not renewable, unsustainable and biological accidents.

What is fossil fuel?

Fossil energy is all that comes from the burning of so-called fossil fuels. These fuels are formed by the remains of plant and animal organisms accumulated in the subsoil of our planet.

climate change; this is because when they are burned they release into the atmosphere the gases responsible for the greenhouse effect.they are not renewable; there are finite resources available and its reserves are not replenished naturally.unsustainable, which means that any burn of fossing fuels contribute to the pollution of the air by CO2.biological accidents over the time, such as pipeline leaks, exploding drilling platforms, and the dumping of millions of gallons of oil into the ocean.

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__________ is the name of the specialized enzyme that unzips the bonds between bases.

Answers

Helicase is the name of the specialized enzyme that unzips the bonds between bases.

By severing the hydrogen bonds between base pairs and unwinding the DNA molecule's two strands, an enzyme known as Helicase aids in unzipping the molecule. It binds to and dissolves the hydrogen bonds connecting the bases on the DNA strands. These hydrogen bonds continue to be broken as the helicase travels along the DNA molecule, separating the two polynucleotide chains.

Primase, a different enzyme, momentarily binds to each strand when the helicase separates them in order to build a foundation upon which replication can start.

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A type of selection that exists between certain inherited conditions and environmental pressures, such as between sickle cell anemia and malaria, that stabilizes the frequency of both alleles is called

Answers

Natural selection is a type of selection that exists between certain inherited conditions and environmental pressures.

How does malaria and sickle cell anemia show natural selection?

The process through which populations of living things adapt and change is known as natural selection. A population's members are naturally varied, which means that they are all distinctive in some ways. This variety indicates that some people have characteristics that are more environment-appropriate than others. Natural selection is a non-random difference in reproductive output among replicating entities.

It turns out that HbS carriers have been naturally chosen in these regions because the trait gives some malaria resistance. When they are infected with the malaria parasite, their red blood cells, which include some aberrant hemoglobin, have a propensity to sickle. The malaria life cycle intensifies both natural selection and random genetic drift.

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____________________ is a condition in which there is widespread scaling of the skin, often with pruritus, erythroderma, and hair loss.

Answers

Erythroderma  is a condition in which there is widespread scaling of the skin, often with pruritus, erythroderma, and hair loss.

Erythroderma, also sometimes called exfoliative dermatitis, is a severe and potentially life-threatening condition that presents with diffuse erythema and scaling involving all or most of the skin surface area .

Causes of erythroderma

A complication of atopic dermatitis, psoriasis, pityriasis rubra pilaris, or another skin condition.A reaction to medicines such as penicillin, barbiturates, or sulfonamide.Certain types of cancer such as lymphoma.

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If one day you are less able to recognize familiar sounds, this lobe of the cortex is probably at fault?

Answers

If one day you are less able to recognize familiar sounds,  Temporal lobe of the cortex is probably at fault.

One of the cortex's four main lobes is the temporal lobe. It is primarily in charge of deciphering the sounds coming from the ears and is crucial for understanding and using language. The temporal lobe collaborates with other neural regions to form fresh, long-term memories, and it aids in object recognition as well.It is also thought that the temporal lobes are crucial for processing affect/emotions, language, and some facets of visual perceptionThe left side of the dominant temporal lobe, which is the side in most people, is involved in verbal learning and memory as well as language comprehension.People who suffer temporal lobe lesions have trouble categorizing words, sounds, or visuals. Damage to the temporal lobe can have an impact on language.

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The human body is uniquely designed to respond to stress and, if necessary, make changes to maintain optimal health and physiological functioning. What is this process called?

Answers

The human body is uniquely designed to respond to stress and body's tendency to monitor ans maintain internal stakes, such as temperature or blood sugar, at fairly constant and stable.

In Homeostasis is an organism's ability to regulate various physiological process to keep internal states steady and balanced. Its helps in maintain the internal environment without being overcome by external stimuli that exist to disrupt the balance.

Homeostasis is the process by which body react to changes in order to keep conditions inside the body.The ability to maintain the temperature of human body is good example of homeostasis which is maintained by controlling the mechanism of functioning  of organs  and tissues/ cellular level , which includes activation or inhibition of individual enzymes.

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What are viable explanations for the consistent observation of a few black mice on the island?

Answers

They undergone genetic mutation that influenced their fur color.

Mutations result either from accidents during the normal chemical transactions of DNA, often during replication, or from exposure to high-energy electromagnetic radiation (e.g., ultraviolet light or X-rays) or particle radiation or to highly reactive chemicals in the environment. Mutation can be of 4 types Germline mutations occur in gametes. Somatic mutations occur in other body cells. Chromosomal alterations are mutations that change chromosome structure. Point mutations change a single nucleotide. Frameshift mutations are additions or deletions of nucleotides that cause a shift in the reading frame. Factor that influenced  mutation are the size of the gene, its base composition, its position in the genome, and whether or not it is being actively transcribed influence its mutation rate.

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