All of the following are structural parts of the CRISPR-CAS9 two component system, except:
A. PAM sequence
B. single stranded guide RNA
C. spacer
D. an endonuclease
E. hairpin loop
F. single stranded tracer RNA

Answers

Answer 1

All of the following are structural parts of the CRISPR-CAS9 two component system, except are hairpin loop and single stranded tracer RNA. So, option E and F are correct option.

The CRISPR-Cas9 system is a powerful gene editing tool that has revolutionized the field of genetics. It consists of two main components: a Cas9 endonuclease enzyme and a single guide RNA (sgRNA).

The Cas9 enzyme acts as a molecular scissors, while the sgRNA provides specificity by guiding it to a specific DNA sequence to be cut.

The option (A) PAM sequence is a short DNA sequence adjacent to the target site that is necessary for Cas9 to bind and cleave the DNA. The PAM sequence is typically a short sequence of nucleotides such as NGG, which is recognized by the Cas9 protein.

The option (B) single stranded guide RNA is a synthetic RNA molecule that is designed to be complementary to the DNA sequence being targeted. The guide RNA provides specificity by guiding the Cas9 enzyme to the correct location in the DNA.

The option  (C)  spacer is the part of the guide RNA that is complementary to the target DNA sequence. The spacer is usually about 20 nucleotides long and determines the specificity of the CRISPR-Cas9 system.

The option (D) endonuclease  is the Cas9 protein that is responsible for cleaving the target DNA at the specified location. The endonuclease is guided to the target site by the guide RNA.

The option (E) hairpin loop is not a structural part of the CRISPR-Cas9 system. It is a structure formed by single-stranded RNA that folds back on itself to form a loop. Hairpin loops are commonly found in RNA molecules and can play a role in RNA processing and stability.

The single stranded tracer RNA (F) is also not a structural part of the CRISPR-Cas9 system. It is a type of RNA molecule that is used to track the movement and processing of other RNA molecules in the cell.

Therefore, the answer is option E. hairpin loop and F. single stranded tracer RNA are not structural parts of the CRISPR-Cas9 system.

For similar question on single stranded tracer RNA

https://brainly.com/question/26599082

#SPJ11

Answer 2

E. hairpin loop. The CRISPR-Cas9 system is a powerful genome editing tool that has revolutionized the field of molecular biology. It is a two-component system that includes the Cas9 protein and a guide RNA (gRNA) molecule.

The Cas9 protein acts as an endonuclease that cuts the target DNA sequence, while the gRNA molecule provides the specificity of the system by guiding Cas9 to the correct location in the genome.

The PAM (protospacer adjacent motif) sequence is a short DNA sequence that is required for Cas9 to bind and cleave the target DNA. The PAM sequence is located adjacent to the target DNA sequence and provides the specificity of the system by preventing Cas9 from binding and cleaving non-target DNA.

The spacer is a short DNA sequence that is derived from a previous exposure to foreign DNA (e.g., a virus or plasmid). The spacer sequence is integrated into the CRISPR array, which is a collection of repeat sequences separated by spacers. The CRISPR array provides the memory of the system by storing a record of previous exposures to foreign DNA.

The single-stranded guide RNA (sgRNA) is a synthetic RNA molecule that is designed to target a specific DNA sequence. The sgRNA is composed of a target-specific sequence that binds to the target DNA sequence and a scaffold sequence that binds to the Cas9 protein.

The hairpin loop is a structure that is formed by the sgRNA molecule, which helps to stabilize the interaction between the sgRNA and the target DNA sequence.

The single-stranded tracer RNA is not a structural part of the CRISPR-Cas9 system.

To know more about DNA

brainly.com/question/264225

#SPJ11


Related Questions

1. What are the different properties of light that apply to the image formation of
optical devices such as mirrors and lenses?​

Answers

Answer:

Optical instruments are based on optics. They use mirrors and lenses to reflect and refract light and form images. The light microscope and telescope use convex lenses and mirrors to make enlarged images of very tiny or distant objects. A camera uses a convex lens to make a reduced image of an object.

The property of light that is important to the image formation in mirrors is reflection. The property of light that is important in the formation of an image by lenses is refraction.

Light refers more specifically to the portion of the electromagnetic spectrum that is perceivable with the optical eyes. There are several properties of light such as reflection, refraction, diffraction, interference, etc.

The property of light that is important to the image formation in mirrors is reflection. The property of light that is important in the formation of an image by lenses is refraction.

Learn more: https://brainly.com/question/865531

PLEASE HELP ASAP Match each word with the phrase that best defines it.
informal
a statement that is objective or unchanging
fact
done in a way that is friendly or casual
formal
a statement that is subjective or based on
interpretation
topic
done in a way that is suitable, appropriate,
or based on guidelines
opinion
the main point of a given subject

Answers

Answer:

fact: a statement that is objective or unchanging

informal: done in a way that is friendly or casual

formal: done in a way that is suitable, appropriate,

or based on guidelines

opinion: a statement that is subjective or based on

interpretation

topic: the main point of a given subject

Match each word with the phrase that best defines it.

1. Fact: a statement that is objective or unchanging

2. Informal: done in a way that is friendly or casual

3. Formal: done in a way that is suitable, appropriate, or based on guidelines

4. Opinion: a statement that is subjective or based on interpretation

5. Topic: the main point of a given subject

What are Phrases?

A phrase is a group of words or a singular word which functions as a grammatical unit. For example, the English expression "the very happy boy" is a noun phrase containing the adjective phrase "very happy".

It can be a single word or a complete sentence. Phrases are used to describe the people, things, or events.

There are following types of phrases. They are:

Noun phrase.Adjective phrase.Adverb phrase.Verb phrase.Prepositional phrase.Gerund phraseInfinitive phraseParticipial phrase

Thus, matching the following words with its phrases

1. Fact: a statement that is objective or unchanging

2. Informal: done in a way that is friendly or casual

3. Formal: done in a way that is suitable, appropriate, or based on guidelines

4. Opinion: a statement that is subjective or based on interpretation

5. Topic: the main point of a given subject

Learn more about Phrases, here:

https://brainly.com/question/15806900

#SPJ2

PLEASE HELP ME!!!!

What would happen to the members of a food web if most of the trees died?
A. only the trees will be effected
B. only things that eat tree leaves will have less to eat
C. Nothing will happen
D. The whole food web will be disrupted

Answers

D is the correct answers
D is the right response

1. DNA 2. Helicase 3. DNA Polymerase 4. DNA Replication 5. Pyrimidine a. Double stranded molecule that has a deoxyribose sugar. b. The end-product of this process are two identical copies of DNA. c. Enzyme that breaks hydrogen bonds to unwind and unzip DNA. d. Nitrogen containing base that has a single ring as its molecular structure. Thymine and Cytosine are an example of this type of molecule. e. Enzyme that covalently bonds sugars and phosphates during DNA replication.

Answers

Answer:

1. DNA-A.Double stranded molecule that has a deoxyribose sugar.

2. Helicase- C. Enzyme that breaks hydrogen bonds to unwind and unzip DNA

3.DNA Polymerase- E. Enzyme that covalently bonds sugars and phosphates during DNA replication

4.DNA Replication-B. The end-product of this process are two identical copies of DNA.

5.Pyrimidine-D. Nitrogen containing base that has a single ring as its molecular structure. Thymine and Cytosine are an example of this type of molecule.

Explanation:

What does a mass extinction look like in the fossil record?​

Answers

There is less diversity hope this helps

Answer:

There is less diversity in the fossil record

Explanation: when compared to older rock layers the fossil record will be less diverse

Give the one chain to the following DNA AATAGGTACCCATGTGCA To write the complementary dna chain. How many nucleotides does this molecule have in total? How many are the bonds that unite nucleotides together?

Answers

Answer:

AATAGGTACCCATGTGCA (original DNA sequence)

TTATCCATGGGTACACGT

Explanation:

Adenine (A) pairs with Thymine (T). Guanine (G) pairs with Cytosine (C). There are 18 nucleotides in this sequence, as seen by the number of base pairs there are. Hydrogen bonds hold together the matching base pairs.

1 point
Which explanation best identifies the relationship between mitosis and
reproduction? *
Mitosis is a form of sexual reproduction because the daughter cells form from one
single parent cell.
Mitosis is a form of sexual reproduction because the daughter cells are genetically
different from the parent cell.
Mitosis is a form of asexual reproduction because the daughter cells form a new
nuclear membrane after reproduction.
Mitosis is a form of asexual reproduction because the daughter cells are genetically
identical to the parent cell.

Answers

muscle of the prada’s


Which statement is true regarding mitosis?
A. 2 cells are made from one cell
B. daughter cells have 1/2 of the original DNA
C. occurs only in sex cells
D. 4 cells are made from one cell.

Answers

Answer:

A. 2 cells are made from one cell

Help with this plz
Thanks. :)

Answers

If a mutation results in an organism with new characteristics then eventually a new species will be formed if more such mutations will continue to accumulate in the individual. Mutations result into the accumulation of variations in an individual and when such variations keep on accumulating in a particular organism consistently it leads to formation of a new species or we can say that evolution has occured.

A mutation is a random change in DNA which therefore affects a gene and/or chromosome. Most mutations have no effect on the phenotype. Some influence phenotype to some extent. Very few create a new phenotype. Mutations can be inherited and therefore passed on from one individual to another. If a mutation causes a new phenotype that makes an organisms better suited to a particular environment, it can lead to rapid change in the characteristics of the individuals in that species.

Hope this helps

describe in on way in which the body gets rid of lactic acid

Answers

lactic acid buildup is a harmless response to strenuous exercise and will go away on its own. Once the body has used the resulting lactate for energy, the liver breaks down any excess in the blood.

In rabbits, straight ears (E) are dominant to floppy ears (e). Two rabbits are crossed, and 50% of their offspring have floppy ears. Which cross represents the genotypes of the parents?

Answers

Ee and ee because when you do the punnet square you get 50% Ee which are straight ears and 50% ee which are floppy ears.

PLS HELP I'LL GIVE THE BRAINLEST!!!
The lineage of pea plants produced round seeds for four generations. The plants that fertilized these pea plants also produced round seeds. However, in the fifth generation, the plant produced to two plants with wrinkled seeds. Can that be possible? Explain your answer using your pedigree chart.​

Answers

Answer:

Explanation:

This happened because two fully recessive plants where introduced into the lineage. these plants where paired with the dominate verison. this would make all of the offspring have the two traits. this being said it would make it possible for the offspring to be Wrinkled Seeds.

When two heter0zyg0us individuals are crossed -simple d0minant inheritance-, or a heter0zyg0us individual is crossed with a h0m0zyg0us recessive one, they can produce h0m0zyg0us recessive subjects among the progeny. Heter0zyg0us individuals among the fourth generation got crossed with another plant (h0m0zyg0us recessive or heter0zyg0us) and produced two h0m0zyg0us recessive plants expressing wrinkle seeds.

---------------------------    

The first step is to understand the given information. So,

The first four generations produced round seedsPlants that fertilized these plants also produced round seeds (see generation II)  Among the fifth generation there are two plants with wrinkled seeds

Let us assume that a diallelic gene determines the shape of seeds.

D0minant allele R codes for round seedsRecessive allele r codes for wrinkle seeds

Now, let us analyze the pedigree. According to the information provided here, we can tell that

black figures represent h0m0zyg0us d0minant individuals, grey figures represent heter0zyg0us individualsempty figures represent h0m0zyg0us recessive individuals

Remember that Generations are represented with roman numbers.

We will name the plants with numbers from 1 to 26.

According to the information in the statement and the information in the pedigree, we can say that grey individuals from the fourth generation are heter0zyg0us expressing round seeds. They can produce wrinkle seeds, if they are fertilized by another heter0zyg0us plant or a h0m0zygous recessive one.

Option 1:

Two heter0zyg0us plants are crossed, and their offspring have wrinkled seeds.

Option 2:

One heter0zyg0us plant is crossed with a h0m0zyg0us recessive one, and their offspring have wrinkled seeds. Let us see the cross

Look at the attached files for a better understanding      

---------------------------------

Related link: https://brainly.com/question/2952835?referrer=searchResults

What are 2 characteristics of index fossils?

Answers

A useful index fossil must be distinctive or easily recognizable, abundant and have a wide geographic distribution and a short range through time. Index fossils are the basis for defining boundaries in the geologic time scale and for the correlation of strata.

hope this helps :)

Which stage of mitosis occurs the least often and why?

Answers

Explanation:

The Anaphase stage is the shortest phase of mitosis. During this phase, disjunction occurs, and migration of sister chromatids away from each other to the poles of the cell occurs, leading to the formation of daughter chromosomes. Molecular motors use ATP to shorten the spindle fibers attached to each sister chromatid

Explanation:

i hope to like it (:

.....

What is an advantage of biofuels?

Answers

Answer:

Advantages of Biofuels Biofuels are considered a green alternative to conventional fuels, which means that they have more advantages than disadvantages. 1. Biofuels are renewable resources of energy

Explanation:

i have no idea about this

Answers

Answer:

I think it's 4 or 3

Explanation:

Sorry if I'm wrong

Which of the following is an advantage angiosperms and gymnosperms have over mosses?
1. they are seed producing so can populate more areas
2. they can photosynthesize
3. they can use oxygen
4. they do not need water

Answers

3. They can use oxagen

Answer:

they are seed producing so can populate more areas

Explanation:

what happened to the
beak depth of finches born in 1978 compared to those born in 1976? Explain why you
think this occurred.

Answers

Answer:

Why do you think the average beak depth of the birds increased?

Explanation:

Because the drought reduced the number of seeds and finches with bigger beaks were able to eat the larger and harder seeds so more of them survived.

I hope this helps!! god bless!! - Natalia

What is the mass of a box accelerating at 3 m/s^2 applying 36 N of force? Hint: Mass = force / acceleration​

Answers

Answer:

I have attached a picture of me explaining how to find the mass. Hope this helps, thank you !!

Which statements describe how traits are inherited? Check all that apply. An offspring always receives different alleles from each parent. An offspring always receives the same alleles from each parent. An offspring can receive different alleles or the same alleles from each par Traits are inherited when proteins are passed from parents to offspring. Traits are inherited when genes are passed from parents to offspring. ​

Answers

Answer:

Traits are inherited when genes are passed from parents to offspring.

Explanation:

that is the definition of family traits

Answer:

An offspring can receive different alleles or the same alleles from each parent

and

Traits are inherited when genes are passed from parents to offspring

Explanation:

How many times more erosion occurs in a soil with 3% moisture than a soil with 7% moisture is a 15 m s-1 wind?

Answers

Answer:

Twice.

Explanation:

If a soil with 3% moisture has twice the rate of erosion as compared to the soil having 7% moisture if both experience same speed of wind i. e. 15 m/s. This is because moisture held the particles of soil tightly with each other and prevent erosion in the soil so if the moisture becomes half in the soil then the rate of erosion is twice or doubled at constant wind speed.

how do you understand geological hazards?​

Answers

Answer:

Geologic Hazards

Seismic hazards related to earthquakes, including ground rupture/faulting, liquefaction, strong motion, and tsunami.Landslides of all kinds, including seismically-triggered landslides, debris flows, mud flows, and rock falls.Mineral hazards such as asbestos, radon, and mercury.

Explanation:

hope it helps you

please mark me as brainlist

PLSSSSSSS HELPPPPPPP I WILL GIVE BRAINLIESTTTTTTTTTT!!!!!!!!!!!!!!!!!!!!!PLSSSSSSS HELPPPPPPP I WILL GIVE BRAINLIESTTTTTTTTTT!!!!!!!!!!!!!!!!!!!!!PLSSSSSSS HELPPPPPPP I WILL GIVE BRAINLIESTTTTTTTTTT!!!!!!!!!!!!!!!!!!!!!PLSSSSSSS HELPPPPPPP I WILL GIVE BRAINLIESTTTTTTTTTT!!!!!!!!!!!!!!!!!!!!!PLSSSSSSS HELPPPPPPP I WILL GIVE BRAINLIESTTTTTTTTTT!!!!!!!!!!!!!!!!!!!!!PLSSSSSSS HELPPPPPPP I WILL GIVE BRAINLIESTTTTTTTTTT!!!!!!!!!!!!!!!!!!!!!
How do living organisms maintain homeostasis within their bodies?

Answers

Answer:

The body regulates those levels in an example of homeostasis. When levels decrease, the parathyroid releases hormones. If calcium levels become too high, the thyroid helps out by fixing calcium in the bones and lowering blood calcium levels. The nervous system helps keep homeostasis in breathing patterns.

Explanation:

Hope this helps :)) Please mark brainliest :))

Answer:

Look below.

Explanation:

They maintain homeostasis by regulating temp, glucose, toxins, blood pressure, and pH.

Nicole lives in the Arctic which has a temperature as low as –40°C.
(a) What class of food should Nicole consume continuously to adapt herself to the cold temperature?

Answers

Organic and healthy foods.

Oats, bananas, red meats, but STAY AWAY from drugs & alcohol!

How does an organism obtain C6H12O6 and O2 to
undergo respiration?

Answers

Answer:

oxygen is given off during photosynthesis as a waste product

Explanation:

this is something that only plants and some algae and bacteria can do. they take sunlight and combined C02 and H20. they create glucose (C6H1206) and oxygen gas (02).

Does Genetic Modified Organism ( GMO ) make an apple bigger?​

Answers

Answer:

the data only can determine the based on the replica of the fruit.

Explanation:

when fruit is genetically modified it's genetically is copied and the process of growing is sped up. in some since the fruit can change in size due to the result of multiple gene copies.

hope this helps!

2. What might happen to the population of
rabbits if there were no foxes? sc.7.L.17.3
A
the population would increase
8 the population would decrease
© the population would stay the same
there would be no effect
D

Answers

The population would increase since there are no predators

When people living on hills put in concrete barriers, plywood fencing, and drainage pipes, they are trying ______________________

Answers

Answer: slow erosion down

Explanation:

Please help! I promise to give brainiest to the person who helps!!
How are the organs attached to the other body systems?

Answers

the body has levels of organisms that built on each other cells make up tissues, tissues make up organs, and organs make up organs system the function of an organs system

depends on the the integrated activity of it organs for instance digestive system organs corporate to process food

The pituitary gland is most similar to:
A A worker in a factory
B A mail carrier
C The boss of a big office
D A security guard or police officer

Answers

Answer:

C. The boss of a big office

Explanation:

It tells all the other hormones what to do

Have a great day!

Other Questions
in cell c6, before the comma in the iferror function, create a formula without using a function that divides the amount of automobile insurance sales (cell b6) by the total sales (cell b11). calculate the grams of n2 gas present in a 0.513 l sample kept at 1.00 atm pressure and a temperature of 14.7c. lin's family needs to travel 325 miles to reach her grandmother's house at 377 miles what percentage have they completed Consumer goods classes (convenience, shopping, etc.) are based on the:- characteristics of the product.- importance of the products brand name.- buying habits of consumers.- age, income, and occupation of consumers. f(x) is continuous for 0.5 < x < - 0.2 and also has the following values: | 0.5 f(x) | 1 -0.4 1.1 -0.3 1.3 -0.2 1.6 f(x) is continuous for 0.5 if you become fatigued while driving, the best countermeasure is which threat to internal validity occurs due to the drop out of participants from the evaluation or lack of completion of the program in its entirety by the participants? you are going to be a construction project manager to build a new pharmaceutical plant. the project requires that governmental hearings about the end product of the plant be held prior to site preparation. what kind of a dependency is this? the gross requirements for a component are derived directly from its parent's net requirements a. true b. false consider an option with the following data: s = 50, e = 45. if you buy the put for 6, calculate the breakeven stock price Question 4(Multiple Choice Worth 5 points)(MC)Two people described the same experience. One described it implicitly by writing, "I sat in the theater and felt salty drops run from my eyes. "Which sentence below explicitly delivers the same message? The chair gave me allergies. The darkness scared me. The movie made me cry. The water splashed my face. the nurse has instructed a pregnant client in measures to prevent varicose veins during pregnancy. which statement by the client indicates a need for further instruction? How can one manage his or her own behavior and influence the behavior of others in a manner that is consistent with the public interest and the values of democratic governance? Be sure to include motivation, communication, and leadership strategies, among other things, in your discussion. which icon / tool allows you to edit a report toolbar in epic so that it retains your preferences epic How is the interest rate on a payday loan calculated? a. Loan amount divided by total fees b. Total fees divided by loan amount c. Total fees divided by days of loan d. APR divided by 365 Please select the best answer from the choices provided A B C D. Defenetions of hardness and toughnees and metals and steels true/false. people need ethics to help maintain their balance, especially in difficult and contentious situations. approximately when were the upright stones of stonehenge erected? (4 pts) define the following terms: a) decantation b) centrifugation c) supernatant d) precipitate 2. (3 pts) what reagent(s) can be used to identify and confirm ag , hg2 2 , and pb2 ions During the 7th examination of the Offspring cohort in the Framingham Heart Study there were 1219 participants being treated for hypertension and 2,313 who were not on treatment. If we call treatment a "success" create and interpret a 95% confidence interval for the true population proportion of those with hypertension who are taking treatment. 2. Using the above example, way we did not have an initial estimate of the proportion of those with hypertension taking treatment. How many people would we have to have to sample if we want E= .01?