the personality trait called is associated with both depression and abnormalities in the brain's serotonin

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Answer 1

Neuroticism is the personality trait which is associated with depression and abnormalities in the brain's serotonin.

Neuroticism in psychology is considered as the trait disposition to experience negative affects. The negative effects includes anger, anxiety, self‐consciousness, irritability, emotional instability, and depression. People who are suffering with neuroticism tends to have more depressed mood. They usually suffer from feelings of guilt, envy, anger, and anxiety. This feeling occur more frequently and more severely in them than other individuals. People with neuroticism are more sensitive to environmental stress than normal people.

People having with neuroticism sees everyday situations as menacing and major. It is often associated with distress and dissatisfaction. The individuals suffering from neurotic are individuals who are of defensive pessimist.

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Correct question

The personality trait called ________ is associated with both depression and abnormalities in the brain's serotonin.


Related Questions

What was the primary objective of this treaty?

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Treaties are agreements made by and between nations. Wars have been ended, land conflicts resolved, and even new countries have been established thanks to treaties.

What is a treaty?A formal, written agreement that is enforceable under international law is known as a treaty. The majority of the time, it is made by and between sovereign states, however it may also involve other legal entities including businesses, people and international organisations. Among other names, a treaty is often referred to as a protocol, covenant, convention, pact or exchange of letters on a global scale. International law, however, only classifies agreements as treaties if they are enforceable by all parties. The extent to which states are required to abide by the rules, the clarity of the regulations and delegation are the three main criteria that treaties are judged on (the extent to which third parties have authority to interpret, apply and make rules).

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What does pointing to mean?

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Move a finger or an item in one's hand in a specific direction in order to draw attention to (someone or something).

To whom or what is it pointing?

To put it another way, when you point at something, you are signaling it directly; when you point to something, you are merely pointing in its general direction or illuminating a path to it.

In reading, what does pointing to a word mean?

It is possible to verify that the letters on the page correspond to the sounds we pronounce as we read by pointing to the words as we go. Each grapheme is sounded out when there is a mistake. The reader can then go back and review the word while also checking for errors.

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Modified hand to hand steering __________ require that the driver place one hand over the other while going into and coming out of the turn.

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Modified hand to hand steering does not require that the driver place one hand over the other while going into and coming out of the turn.The releasing of brake pressure from the brake pedal allowing the low idle of the engine to move the vehicle forward is known as engine acceleration.

Hand-to-hand steering referred to a techniques of steering in which driver gets permits to make steering inputs while keeping both hands on the wheel. Modified steering means to use this code if we need to use any of the following adaptations to our vehicle.

Adapted steering wheel means to reduced in a thicker or larger steering wheel section that adapted position of the steering wheel for operating steering.

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To develop the most persuasive content for a communication, what must first be understood by the communicator?

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What kind of material will best motivate the audience?, according to the first communicator, in order to provide the most persuasive content for a communication.

What is the most effective technique to engage and persuade an audience?

One of the most powerful persuasion techniques is the use of emotive language in speaking. Choose phrases and words that will cause your readers to feel a certain way. Emotional triggers are situations, events, or memories that cause a strong emotional reaction.

What is the first task of the most persuasive messaging?

In most persuasive writing, the first stage is to get the reader's attention. There are several ways to do this, such by asking a rhetorical question, providing an interesting or fascinating information, revealing an eye-catching statistic, presenting a challenge, or posting a testimonial.

What do people believe to be the most crucial element of persuasion?

The most important aspect of your presentation is undoubtedly its pathos, which concentrates on its emotional content. You can only emotionally sway someone if you want them to adopt a different viewpoint or do a particular action.

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____________________ are groups of individuals who put a plan in place before an ethical crisis occurs.

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Ethics committees are groups of individuals who put a plan in place before an ethical crisis occurs. In decision making ethically are responsible to determine the facts of the situation that making an honest effort to understand facts from different opinion.

The ethics committee members of roles and responsibilites is to protect the subjects that involved the study and also considered the possible risks to the environment and community.

The Ethics Committees gives an advice on moral questions in education, clinical care or staff and the public issues in medical ethics, and develops policies related to care of patient.

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Which of the following types of studies require approval by an
Internal Review Board? (Pick more than one)
1. research that poses risks to participants
2. surveys not meant to be published
3. data collected for instructional purposes only
4. data collected through phones or computers
5. data collected on vulnerable populations

Answers

Research that poses risks to participants and data collected on vulnerable populations require approval by an Institutional Review Board. Hence, options (1 and 5) are considered to be correct.

Give a brief account on Institutional Review Board.

The Institutional Review Board (IRB) is a management body established to protect the rights and welfare of people chosen to participate in research projects run by the institution to which it is connected. Before starting, the IRB must review every study involving human beings, regardless of whether it is funded or not. The IRB is concerned with the safety, rights, and privacy of human beings. The IRB has the authority to approve, exempt, disapprove, monitor, and require adjustments in any research activity that falls within its purview, in accordance with institutional policy and federal legislation.

The IRB must include at least five members with a diversity of educational and professional experiences in order to adequately and thoroughly examine human research and its institutional, legal, scientific, and social repercussions. The Board must also include at least one member who is not a scientist and one member who is not connected to the institution. The IRB has a number of experts on staff who consult with the Board and occasionally take part in protocol evaluations.

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What happens in a communist society?

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In a communist society, everyone shares the benefits of labor and the state controls all property and wealth.

A communist society is one that is based on a collective ownership of all resources, including the means of production. It is driven by the idea that every individual should contribute according to their abilities and be rewarded based on their needs. It promotes economic and social equality for all and aims to minimize the gap between the wealthy and the poor.

This type of system does away with class divisions and the private ownership of capital, thus providing everyone with an equitable share of the resources and the fruits of labor. It seeks to ensure the equitable distribution of goods and services, and seeks to ensure that everyone has access to the basic necessities of life.

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Why did Japan bomb Hawaii?

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Japan planned to use attack as preventive measure to stop United States Pacific Fleet from interfering with its planned military operations in Southeast Asia against overseas territories.

What is military?

A military is a strongly equipped, highly organized force that is primarily designed for combat, sometimes known as the "armed forces" collectively. Its members are often recognized by its distinctive military uniforms, and it is typically approved and maintained by a sovereign state. Military housing, schools, utilities, logistics, hospitals, legal services, food production, finance, and banking services are all provided specifically for military personnel. A nation's military may also operate as a distinct social subculture. More ancient than written history itself is the occupation of being a soldier in a military. Classical antiquity's military leaders are depicted with force and prowess in some of the most iconic artworks. One of Ramses II's defining moments was the Battle of Kadesh in 1274 BC, which is commemorated in bas-relief on many of his monuments.

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What did the Magna Carta led to?

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The Magna Carta led to the declaration that the king and the government in Britain is not above law.

The Magna Carta was enacted within the parliament of United Kingdom in the year 1215 and it was signed by the then king. This document granted several provisions of law and justice and reformed the earlier provisions of law and justice. It guaranteed that the King is not above law and the provisions for law are same for all the citizens including the king. The Magna Carta also established the law of equality before the law as it allowed the citizens to get justice before the law by enabling trial before imprisonment. It also regulated all the previous provisions and included new provisions.

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Why were most Americans more prosperous than Europeans during the 1920s?
A) Americans worked harder than Europeans.
B) Corrupt European business leaders hoarded the profits.
C) Europe was recovering from the destruction of World War I.
D) Americans were more technologically savvy than Europeans.

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Answer:

C) Europe was recovering from the destruction of World War I.

Clinical decision-making that integrates the best available research evidence and clinical expertise in the context of the cultural background, preferences, and characteristics of clients is called:

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Substantiation- grounded practice( EBP). EBP is an approach to clinical decision- making in which healthcare providers use the stylish available  exploration  substantiation, clinical  moxie.

This approach allows healthcare providers to  give the loftiest quality of care to their cases. To effectively use EBP, healthcare providers must be substantial grounding knowledgeable of the  colorful aspects of clinical  exploration, including the strengths and limitations of different study designs and the interpretation of  exploration results. likewise, healthcare providers must also be willing to  unite with cases and families to understand their individual backgrounds, preferences, and characteristics in order to  conform care to their  requirements. This is especially important when addressing artistic considerations, as different  societies have different beliefs, values, and preferences. By integrating the stylish available  substantiation, clinical  moxie, and case preferences, healthcare providers are more  suitable to  give personalized care that's more likely to affect in better health  issues for their cases.

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Lawrence Kohlberg felt that one of the only ways individuals will accomplish the objectives in each of his six stages was to participate in __________ in small group settings. brainly

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Lawrence Kohlberg believed that participating in consensus democracy in small group settings was one of the few ways individuals could achieve the objectives in each of his six stages.

Lawrence Kohlberg's moral growth phases are an adaption of a psychological theory developed by Swiss researcher Jean Piaget. Kohlberg began working on this idea as a doctoral student in psychology at the University of Chicago in 1958 and developed on it throughout his life. According to the idea, moral thinking, which is a required condition for ethical action, has six developmental phases, each of which is better at responding to moral quandaries than its predecessor. Kohlberg researched the evolution of moral judgment considerably beyond the ages previously studied by Piaget, who also maintained that logic and morality evolve in phases.

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Answer:

The answer is A.

Explanation:

What are the effects of digital society?

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Explanation:

There are many side effects such as technology addiction, time loss, isolation, lower academic performance together with its benefits. It is obvious that it is not easy and rational way to entirely keep students away from social media.

What was the main purpose of the Second Continental Congress?

Answers

The main purpose of the Second Continental Congress was to lead a formation of a national government that governed under the significance of de facto principles.

The Second Continental Congress was an official body formed during the eighteenth century. The main intention of the formation of this Congress was to lead revolutionary wars against the English colonists in the American society. This body was also the one that declared the American independence under the guidance and leadership of Jefferson.

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Human beings have long been migrants, moving themselves, their material goods, and even ideas from one part of the world to another. What makes this process, which is now called globalization, seem so different today than in the past

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Moment, the process of globalization is much different than it was in the  history due to advances in technology, changes in  profitable and political systems, and the increased interconnectedness of the global frugality.  

One of the main differences between globalization  moment and in the  history is the speed with which it takes place. Advances in transportation and communication technology have made it much easier and faster to travel vast distances and to communicate with people  each over the world. This has made it possible for people to resettle and for goods to be  packed  and traded across the globe in a matter of days.   Another difference is that globalization is now much  further  connected than in the  history. The global frugality is decreasingly  connected, meaning that changes in one country can have  wide  goods on other  husbandry. This has made it easier for ideas, goods, and people to move between countries, leading to increased artistic exchange and  profitable growth.  

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Many sociologists study innovation. Why would this MOST likely enhance their research?
A.) Sociologists can use new items like a computer to type research papers.
B.) New products and ideas play a big role in the evolution of culture.
C.) Culture rarely changes when innovation occurs.
D. Sociologists believe that innovation will die off very soon.

Answers

the correct answer is b

What was one major outcome of the non-aggression pact between the Soviet Union and Germany?

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The sole and most significant result of the non-aggression agreement reached between Germany and the Soviet Union prior to the outbreak of World War II was the Germans' ability to operate freely in Eastern Europe.

What is aggression?

Hostility is an overt or covert social engagement that is typically detrimental with the intention of injuring or inflicting other harm to another person, despite the fact that some people can direct their aggression into creative and constructive outlets. Direct aggression and indirect aggression are the two categories that characterize human aggressiveness. While indirect aggression is described as behavior intended to harm a person's or group's social ties, direct aggression is defined as physical or verbal action intended to harm another person. These tactics are typically motivated by emotions like fear, rage, anger, domination, wrath, tension, or pleasure. In addition to verbal or nonverbal communication, hostility can take several forms, including anti-predator aggression, defensive aggression, dominance aggression, inter-male aggression, and aggression triggered by brain stimulation.

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Why do American government buildings such as the US Capitol and the White House use neoclassical style?

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The Neoclassical movement was pretty crucial to early Americans. One of the most influential American architects to first embrace this style as a link between the American ideas of republican government and the legacy of ancient Rome was Thomas Jefferson.

Neoclassical art was familiar across many parts of Europe, especially in architecture. However, where it really grabbed root and took grasp wasn't in Europe, but in a brand-new nation called the United States of America. The Americans became quickly gripped with Neoclassicism, both before and after their revolution, and it evolved into a symbol of the American nation. The founding figures disseminated an obsession with ancient Rome. Ancient Rome was the only true example of a prominent Republic in Western history.

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In Hungary, as in much of Eastern Europe, an overwhelming proportion of women work, many of which are in middle management and light industry.

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It is completely accurate and factually appropriate to mention that the overwhelming proportion of working women are in the middle management and light industry in Hungary, as in much of the Eastern European region. Therefore, the statement given above is true.

The proportion of working women increased in the European society, especially after the modern age and scholar mindset grew into the roots of the society. This is because male workforce would carry out artistic or skilled labor as their primary occupation and women had to assume roles in the middle management and other lighter industries.

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Which of the following is NOT a research-based finding about source credibility? (10 points)
a. The introduction of a speaker by another person can increase the speaker's credibility.
b. The way the other person introduces you can increase or decrease your credibility in the eyes of the audience.
c. The speaker's perceived status can increase or decrease source credibility.
d. Audiences are mercifully slow in deciding a speaker's status or source credibility.

Answers

Option (d), audiences are mercifully slow in deciding a speaker's status or source credibility  is not a research-based finding about source credibility.

What are the three components of source credibility?

According to the source credibility idea, individuals are more likely to accept a source's arguments if they appear trustworthy. Three aspects of the credible source are looked at: The three qualities of competence, reliability, and likeability highlight how social media influencers can develop trust and rapport with their audience.

The aspects of credibility that contribute to the establishment of referent power are character, poise, extroversion, and sociability. The quality of the arguments in the message or any other information the recipient deems pertinent to those attitudes is likely to be the basis for the recipient's opinions if they have the capacity and desire to analyze the problem.

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Jazz is determined to quit drinking and enters a therapy program. The program places a nausea-inducing drug into each drink she takes. After a few weeks, the sight or thought of a drink makes Jazz sick. Her sickness as a result of the drug is a(n)

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Jazz is determined to quit drinking and enters a therapy program. The program places a nausea-inducing drug into each drink she takes. After a few weeks, the sight or thought of a drink makes Jazz sick. Her sickness as a result of the is UR drug .

Organisms pick up lessons from their actions' results. A behavior is either encouraged or reinforced through a succession of rewards and punishments in operant conditioning.

As a result, anytime your child sees you arrive at home wearing a baseball cap, he becomes delighted because he associates it with going to the park. This classical conditioning is learning through association. He distinguished between positive reinforcement (a behavior that is increased by anything like praise or reward) and negative reinforcement, which are, of course, the two sorts of reinforcement .

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ASAP


Essay on Climate Change in your own words.

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Answer:

Climate change is a shift in the region's typical weather patterns. This could indicate a shift in the typical annual rainfall for a location. Alterations to a location's typical temperature for a month or season are another possibility.Climate change also refers to a shift in the planet's climate. This could be a deviation from the average temperature of Earth. Alterations to where rain and snow typically fall on Earth could also be the cause. In a few of hours, the weather can shift. Changes in the climate might take hundreds or even millions of years.

Which suffragist was selected to represent their state in the U.S. Capitol National Statuary Hall and what state are they from

Answers

Martha Hughes Cannon was selected to represent their state in the U.S. Capitol National Statuary Hall and she was from Utah.

The United States Capitol National Statuary Hall is a chamber located in the United States Capitol in Washington, D.C. It is a large, two-story, semicircular room with a gallery along the curved perimeter. The hall is used for ceremonial events and is the home of two statues for each state in the United States.

The statues are donated by the state and represent prominent citizens from the state's history. The National Statuary Hall is a beautiful and important part of the United States Capitol and has been the site of many important events in American history.

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Define the process of shaping, or successive approximations, and explain how these principles could be used with the positive reinforcer you have already described.

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Shaping is the process of encouraging repeated attempts to imitate a desired behavior. In particular, when utilizing a shaping strategy, each approximate demonstration of the desired behavior receives reinforcement, but non-approximations of the desired behavior do not.

Parents' lavish praise and attention are the most common kind of reinforcement. Teaching a toddler to wash his teeth is another illustration. When a child receives praise for improving at brushing their teeth, shaping is taking place.

When teaching handwriting, the shape is used to reinforce consecutive approximations. Long before we reach letters, we may begin with a scribble, move toward a line, then move toward a shape.

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sandi and kyle are in your office break room, having what looks like an intense conversation. as you approachto try to

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Sandi and kyle are in your office break room, having what looks like an intense conversation. as you approach try to be calm and listen to them.

In an intense conversation, psychologist Matthias Mehl at the University of Arizona approaches conversations, and he defines sandi kyle's conversation as small talk on the basis of how many details are exchanged. ‘If afterward, I know nothing more about you than I knew before,’ he tells me, ‘then that will be small talk.’ The vacuousness of small talk helps to explain why it’s often so boring, but it can be worse than that, unfortunately, both boring and awkward.

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In the context of work flow design, which of the following best describes a position?
A. the set of duties performed by a person
B. a set of related duties fulfilled by many employees
C. an aggregate of similar jobs
D. the set of skills and abilities that is required of a person in a job
E. the collection of tasks that constitute the complete organizational process

Answers

In the context of work flow design,  the set of duties performed by a person best describes a position.

What exactly is a work flow analysis?Utilized to get a broad overview of what is happening within the company. Outputs, then actions, then inputs, should come first.Workflow analysis involves five phases. Collect information about the affected workflows first, then identify them. Examine the statistics after that, and then make adjustments to the trouble spots. Create a timetable to oversee these activities and modify them as necessary.It aids in their evaluation of the tasks necessary to produce a good or deliver a service. Any work unit's products may be identified using work flow analysis.In the context of work flow design,  the set of duties performed by a person best describes a position.

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Which of the following is not an example of judicial review of an athletic association decision?
O The decision involves an on-field decision by an umpire or referee.
O The decision violates public policy because it is fraudulent.
O The decision exceeds the scope of the athletic association's authority.
O The athletic association breaks one of its own rules.

Answers

The decision involves an on-field decision by an umpire or referee, is not an example of judicial review of an athletic association decision.

Why are governing bodies in sports significant?

The governing bodies in sports control and manage the surroundings of its sport, administer the sport's practice and involvement, enhance its sport, and influence both its members and the organizations it belongs to. The governing body of a sport may have a governmental name, yet it is not in any sense governmental.

Because it is a private organization, the governing body of a sport is not subject to judicial examination. Governing bodies exercise only private powers, as determined by the 1992 case of R v. Jockey Club. A number of attempts to submit sports regulating organizations to judicial scrutiny were defeated with the help of law, which was a key authority.

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How does the Fourth Amendment protect citizens from the government complete the following statement?

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The Fourth Amendment of the Constitution safeguards citizens from arbitrary searches and seizures. Without a signed search warrant granted on the basis of probable cause, it is illegal to search someone's house or personal belongings.

The Fourth Amendment of the Constitution safeguards citizens from arbitrary government searches and seizures. Only those searches and seizures that are ruled legally unreasonable are protected by the Fourth Amendment, though. Three key topics are covered by Fourth Amendment case law: what defines "searches" and "seizures" by the government, what justifies such searches and seizures, and how to handle Fourth Amendment rights violations. Early court rulings restricted the amendment's application to physically interfering with people or property, but Katz v. United States changed that (1967)

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what are the cybersecurity terms used to describe the two types of insider threats?

Answers

These dangers could be direct or covert. People that act in a way that compromises the targeted organization are considered direct threats. System weaknesses that expose resources to unintended or malicious threat actors are known as indirect threats.

Which two categories of insiders best describes them?

the irresponsible insider. The most typical kind of insider is the thoughtless one.

The ignorant insider

A Saboteur.

the traitorous insider.

the side hustler.

the mollusk.

What are the two categories of online safety?

security for vital infrastructure.

security for applications.

network safety

Cloud protection.

security for the Internet of Things (IoT).

Which phrase best sums up an insider threat?

Anyone who has access to a company's physical or digital assets is considered to be an insider danger. Insiders are anyone with authorized access to a company's network and computer systems, including current employees, past employees, contractors, vendors, or business partners.

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what hairpiece has a base that covers the crown, occipital and nape area?
a. fall
b. braid
c. switch
d. chignon

Answers

A fall is a hairpiece with a base that covers the crown, occipital and nape areas.

Hence, option (a) is the correct choice.

3/4 wigs, or 1/2 wigs, are hairpieces that you attach to your hair in two places: directly in front of your crown and at the nape of your neck. They are meant to mix in with your natural hair, giving you instant volume.

The interior of the wig is known as the base, although it can also be referred to as the weft, wig foundation, or cap.

A hair topper is often referred to as a half wig or a top piece. This is beneficial when your hair starts to thin visibly. However, the amount of covering you require will depend on the size of the afflicted region on your scalp. Sizes of hair toppers may vary.

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Other Questions
Manish and Ravi are reading the same series of books. As of today, Manish has read a total of 544 pages. If he reads at the same pace, after 8 days he will read a total of 928 pages.The total number of pages that Ravi has read is modeled by the equation y=51x+594, where x is the number of days after today, and y is the total number of pages read.Who will finish the series first? Why?Select the response that correctly answers both questions.ResponsesRavi will finish first, because he has already read more than Manish as of today, and he reads more than Manish each day.Ravi will finish first, because he has already read more than Manish as of today, and he reads more than Manish each day.Ravi will finish first, because even though Manish has read more as of today, Ravi reads faster overall.Ravi will finish first, because even though Manish has read more as of today, Ravi reads faster overall.Manish, because even though Ravi has read more as of today, Manish reads faster overall.Manish, because even though Ravi has read more as of today, Manish reads faster overall.Manish will finish first because he has already read more than Ravi as of today, and he reads more than Ravi each day. Read the excerpt from A Case Against Zoos.Zoo life affects the mental health of animals and it shows in their behaviors. Animals may pace, act aggressively, or become depressed. With nothing to do, they become bored and disinterested in life. Meat eaters, like the lion, can no longer hunt for their food. Elephants are used to walking for miles each day. In zoos, they are confined to small pens and can only walk in circles for exercise. Zoo life harms animals mental and physical health when they cannot behave naturally. Justin is writing an essay on the behaviors of zoo animals. He has already added information from the article The Importance of Zoos about the work of animal behaviorists that helps animals stay active and prevent boredom.He wants to add information that answers this question: What types of negative behaviors can zoo animals develop?Which information from A Case Against Zoos best answers this question?Select the two correct answers. Suppose the value of the price elasticity of demand is -3, What does this mean? y^2=1/5(x-4), (24,2) A diagonal of a polyhedron is a line segment connecting two non-adjacent vertices. How many diagonals does a pentagonal prism have A 5 m 60 cm high vertical pole cat a hadow 3 m 20 cm long. Find at the ame time(i) the length of the hadow cat by another pole 10 m 50 cm high, Elie Wiesel commonlit worksheet what impact does the phrase deportation by cattle car in paragraph 4 have on the readers understanding of the text PLEASE HELP FASTTT! pls put real answer :) Automotive airbags inflate when sodium azide, NaN3, rapidly decomposes to its component elements via this reaction. 2NaN3 2Na + 3N2 ***How many grams of sodium azide are required to form 5. 00 g of nitrogen gas?*** The molar mass of sodium azide is 64. 99 g/mol The molar mass of nitrogen gas is 28. 00 g/mol Show all steps in the solution of this question, including proper units, for full credit Marsh Co. Had 2,400,000 shares of common stock outstanding on January 1 and December 31, 2021. In connection with the acquisition of a subsidiary company in June 2020, Marsh is required to issue 100,000 additional shares of its common stock on July 1, 2022, to the former owners of the subsidiary. Marsh paid $200,000 in preferred stock dividends in 2021, and reported net income of $3,400,000 for the year. Marsh's diluted earnings per share for 2021 should be The influx of unskilled Irish immigrants into New York City in the 1840s and early 1850s drives down wages for other workers at the low end of the salary ladder. Why is the Necessary and Proper Clause so debated? Eric went for a drive in his new car. He drove for 182.4 miles at a speed for 57 miles per hour. For how many hours did he drive? A fifth grader takes a standardized achievement test (mean = 125, standard deviation = 15) andscores a 148. What percent of children made higher than a 148? Which of the following terms is defined as an ideal that embraces all aspects of civilized life? a. criminal justice. b. vigilante justice. c. social justice. d. civil justice. the scale on a map is 1:5000000two towns are 7cm apart on the map work out the actual distance between the towns An infinite line of charge produces a field of magnitude 4.5 ( 104 N/C at distance 2.0 m. Find the linear charge density. What are three things that can prevent one from finishing school work and how might you overcome them? list two reasons explaining why its important to request your 3 credit reports and review them regularly. In NOP, mN=(9x+8)mN=(9x+8) , mO=(4x+13)mO=(4x+13) , and mP=(2x6)mP=(2x6) . Find mN.mN The membrane-bound compartment indicated by structure D contains which of the following?O ribosomes O oxidases and catalases O hydrolytic enzymes O nucleic acids