Writing the Nightingale Pledge was not the work of Florence Nightingale.
What is Nightingale Pledge?The Nightingale Pledge is a modern version of the original pledge that was written by a Mrs. Lystra Gretter in the early 1890s, to honor the work of Florence Nightingale. The pledge is a promise made by nursing students, it is a statement of commitment, compassion, and dedication to the nursing profession.
Florence Nightingale is known for her work during the Crimean War as a pioneer of professional nursing, as well as for founding the first formal nursing program based on both science and clinical experience, also for her book Notes on Nursing which is still considered a classic in nursing literature.
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the diagnostic term that means abnormal build up of calcium on the kneecap (patella) surface is:
The diagnostic term that means abnormal build up of calcium on the kneecap (patella) surface is Calcinosis.
Chondrocalcinosis is a condition in which calcium pyrophosphate crystals accumulate in the joints. It is also referred to as calcium pyrophosphate deposition disease (CPPD). The deposits irritate the cartilage, which damages it by causing inflammation. The calcium may subsequently be partially absorbed by your body. A procedure known as debridement, an arthroscopic operation, can be used to remove the calcium deposits. We can simply regard this term as Calcinosis diagnostically.
Typically, a physical examination by your doctor can identify calcium deposits on your skin. To identify further forms of calcification, your doctor might have to request imaging tests. On X-rays or CT scans, calcium deposits can be seen. A calcium blood test may also be prescribed by your doctor.
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the nurse is teaching the parents how to provide care for their child with sickle cell anemia. which intervention
....should the nurse prioritize in the teaching plan?
The nurse should prioritize teaching the parents about the signs and symptoms of a sickle cell crisis, and how to administer pain medication, oxygen therapy and hydration as needed.
Sickle cell anemia is an inherited disorder that can cause chronic pain, fatigue, and other complications. The parents should be aware of the signs of a sickle cell crisis, such as severe pain, difficulty breathing, and fever, so that they can take appropriate action to provide relief for the child.
YOUARE SCANNING A PATIENT AND NOTE THE PRESENCE OF GALL STONES AND GB WWALL THICKENING. WHAT ELSE SHOULD YOU DO TO DETERMINE IF ACUTE CHOLECYSTITIS IS PRESENT
Images of r gallbladder and bile ducts can be produced using abdominal ultrasound, endoscopic ultrasound, computerized tomography (CT) scan, or magnetic resonance cholangiopancreatography (MRCP). These images can demonstrate symptoms of gallbladder and bile duct stones or cholecystitis.
Your gallbladder becomes inflamed, which is cholecystitis. Gallstones can lead to gallbladder inflammation. The most common cause of cholecystitis is the development of hard particles in your gallbladder (gallstones). Gallstones can obstruct the cystic duct, which is the conduit via which bile exits the gallbladder.Is cholecystitis a significant issue?
It is a potentially dangerous condition that typically requires hospital treatment. A sudden, severe pain that radiates to your right shoulder on the upper right side of your abdomen is the primary sign of acute cholecystitis.
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Choose the correct answer:-
uterovaginal prolapse:
1. very painful condition
2. cervix is often prolonged
3. may cause intestinal obstruction in case of large rectocele
4. improve by erect position
Answer:
2
Explanation:
The cervix is elongated as a result of it's weakness to hold the uterus
Collaborating with specialists is an important part of primary care involving patients with neurologic injuries. It isimportant as an APN to know when to refer to a specialist and what the goal of that referral is: furtherinformation, diagnostic testing or treatment recommendations
It is important as an APN to know when to refer to a specialist when a patient has a neurological injury and the purpose of that referral is for diagnostic testing.
What is a neurological injury?Neurological injury or nerve injury is a disorder that affects parts of the brain and nervous system. There are various types of neurological disorders, namely :
Multiple Sclerosis is a disease thought to be caused by the environment, genetics, and viruses. This disease is usually characterized by a tingling feeling, numbness, or weakness in several limbs.Alzheimer's is a disorder that often occurs in elderly patients and is usually characterized by memory loss in the brain. Parkinson's attacks nerve cells in the middle of the brain which are useful for regulating the movement system in the body.Learn more about the main symptoms of neurological disorders here :
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Audrey has been having fatty stools and pains after eating, especially after eating high fat meals. Which of the following is most likely the cause
The reason Audrey experienced fatty and painful stools after eating, especially after eating high-fat foods, was a bacterial infection in the digestive tract.
What is fatty stool?Fatty stools are referred to as Steatorrhea. Steatorrhea that does not occur for a long enough period of time can be caused by the type of food consumed. It usually occurs after consuming foods with a high content of fat, fiber, and potassium oxalate.
Too much of this content is consumed, causing the digestive system to not be able to break down food properly. It can even be caused by an infection in the digestive tract.
Your question is incomplete. Maybe the point of your question is :
Audrey has been having fatty stools and pains after eating, especially after eating high-fat meals. Which of the following is most likely the cause
Infection in the digestive tractHigh blood pressureStomach acidLearn more about dietary measures for steatorrhea here :
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A 10-year-old child is brought to the emergency department for fever and cough. You obtain an oxygen saturation on the child. What oxygen saturation would indicate that immediate intervention is needed
The immediate oxygen related intervention needed for the child is 88% on 4L of Nasal oxygen.
Oxygen saturation is necessary in the body because it drives all the cells to function properly and within range of efficient working. If oxygen fells below a certain limit, then it may harm essential functions of the body and may be indicative of conditions such as hypoxia. A 88% limit is the lowest safe limit below which the body will respond negatively and the child may seek immediate actions. In cases of excessive coughing, resulting lower carbon dioxide levels limit the amount of oxygen able to get into your bloodstream and around your body. Normal arterial oxygen is approximately 75 to 100 millimeters of mercury.
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b. A 24 year old newly diagnosed with seizures is prescribed phenytoin. The client asks the nurse if she will still be able to take her oral contraceptive medication. How should the nurse respond?
The nurse must respond to the query of the women on oral contraceptive by responding that she must use a different form of birth control while taking phenytoin, which means option B is the right answer.
Oral Contraceptives are the pills which are taken by the women before and after intercourse to prevent the egg from fertilizing. It is one of the most commonly used method to avoid unwanted pregnancy. Phenytoin is the anti-seizure drug which is used to decreasing abnormal electrical activity in the brain. It has some side effects like flu, rashes etc. Phenytoin can reduce the effects of oral contraceptive pills (OCPs) and so the women will have to extra dosage of contraceptives which can be harmful for the body and so she is advised to use another method of birth control.
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To refer to complete question, see below:
A patient is to begin taking phenytoin [Dilantin] for seizures. The patient tells the nurse that she is taking oral contraceptives. What will the nurse tell the patient?
a. She may need to increase her dose of phenytoin while taking oral contraceptives.
b. She should consider a different form of birth control while taking phenytoin.
c. She should remain on oral contraceptives, because phenytoin causes birth defects.
d. She should stop taking oral contraceptives, because they reduce the effectiveness of phenytoin.
A nurse identifies that a client may be dehydrated. Which clinical manifestations would the client exhibit
Answer:
Oliguria dyspnea
Explanation:
Clinical signs of the client include oliguria, hypotension, and Tenting tissue turgor.
Your body loses water on a regular basis through perspiration and urine. You get dehydrated if it is not replenished. Adults at risk include athletes, persons who work in hot environments, the elderly, and those with chronic illnesses.
Dehydration is not limited to athletes who are exposed to direct sunlight. Bodybuilders and swimmers, for example, are among the athletes who frequently get the illness. It is conceivable to sweat in water, as strange as it may appear. Swimmers sweat a lot while they swim.
Water makes up over 60% of a man's bodily weight. It accounts for around half of a woman's weight. Young and middle-aged individuals who drink when thirsty don't usually need to do anything else to keep their body's fluid balance in check. Children require more water because they use more energy, yet most children who drink when thirsty receive the amount of water their systems require. Adults over the age of 60 who drink solely when thirsty are likely to acquire only approximately 90% of the liquids they require.
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which nursing intervention may be particularly beneficial to an African American patient with insomnia
Nursing assistance may be especially useful to an African American patient suffering from sleeplessness due to the low cost of test strips & disposable supplies.
Insomnia is a common problem that can make it difficult to get asleep, difficult to remain asleep, or lead you to wake up early and be unable to sleep again. Because everyone's sleep demands varies, there is no defined amount of sleeping hours required to be diagnosed with insomnia. Adults are generally advised to acquire 7 hours of sleep every night.
The majority of instances of insomnia are caused by poor, sadness, anxiety, a lack of exercise, a chronic ailment, or a specific prescription. Symptoms may include trouble falling or staying asleep, as well as a lack of sleep. Insomnia is the most common problem that really can make it difficult to get asleep, difficult to remain asleep, or lead you to wake up early and be unable to sleep again.
Insomnia treatment includes modifying sleep patterns, behavioural therapy, and recognizing and treating underlying problems. Sleeping medications can also be utilized, but the negative effects should be well watched.
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in january, a 57-year-old man with life-threatening heart disease received the first successful transplant of a ’s heart into a human being, a groundbreaking procedure that offers hope to hundreds of thousands of patients with failing organs.
In January, a 57-year-old man with life-threatening heart disease received the first successful transplant of a pig’s heart into a human being, a groundbreaking procedure that offers hope to hundreds of thousands of patients with failing organs.
In a groundbreaking procedure that gives hope to hundreds of thousands of patients with failing organs, a 57-year-old man with life-threatening heart disease received a heart from a genetically modified pig. It is the first successful human heart transplant from a pig.
After the death in March of a 57-year-old man with terminal heart disease who became the first person to receive a genetically modified pig heart at the University of Maryland, the experiments were made public.
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Should you Hold or Restrain a Person Having a Seizure?
It is not recommended to hold or restrain a person having a seizure.
It is generally not advised to hold or restrain a person having a seizure as it can be dangerous for both the person having the seizure and the person trying to restrain them. Instead, it is important to keep the person safe by removing any nearby hazards such as sharp objects or hard surfaces. Additionally, cushioning the person's head with something soft can help prevent injury. Stay with the person until the seizure is over, and make sure to time the seizure and note any unusual symptoms, if possible. If the seizure lasts longer than five minutes or the person has difficulty breathing, call your local emergency services immediately.
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What's the primary focus of the pharmacy technician?
How are pharmacy technicians required to continue training after graduation?
What’s the difference between a drug’s brand name and generic name?
The primary focus of the pharmacy technician is to process and dispense prescribed drugs (question 1). Pharmacy technicians are required to continue training after graduation because new drugs appear and they need to be correctly prescribed (question 2). The difference between a drug’s brand name and a generic name is the fact that the generic name is not technical.
What is the primary role of a pharmacy technician?The primary role of a pharmacy technician is to provide proper prescriptions for approved drugs for specific patients.
Therefore, with this data, we can see that the primary role of a pharmacy technician is based on the prescription of different drugs, which requires continuous specialization after graduation.
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which form of treatment is used to promote the healing process by dilating blood vessels which allows for more circulation to occur in the affected area.
The treatment used to promote healing by dilating blood vessels and increasing circulation is vasodilation.
What are the benefits of increased blood circulation to an injured area? Increased blood circulation to an injured area can bring a variety of benefits. Firstly, increased blood flow can help to reduce inflammation and swelling. Blood carries oxygen and nutrients to the area and helps to flush away waste products, which can help speed up recovery time. Secondly, increased blood flow can stimulate the body’s natural healing processes. This means that the body can more quickly rebuild and repair damaged tissue. Finally, increased blood circulation to the injured area can help to reduce pain. This is due to the release of endorphins, which are natural pain relievers.Overall, increased blood circulation to an injured area can help to reduce inflammation, stimulate the body’s natural healing processes, and reduce pain. This makes it a vital part of the healing process and can help to speed up recovery and reduce the severity of symptoms.To learn more about treatment refer to:
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During a discussion of concern about approaches used with aggressive patients in the Emergency Department, several staff members express concern for their safety. As a leader, the nurse manager should:
As a leader, the nurse manager must directly talk to the speakers and acknowledge their problems which means option A is correct.
A nurse manager is responsible for the safety of the staff and that they live in healthy environment where they are safe from external aggression which may hurt them mentally or physically. She must look into the matter directly from the people who have faced it or been an eye witness to it. Leadership includes listening patiently to the problems and then coming to a solution which encourages welfarism of both staff and patients who are not able to control their anger. This will boost the effective functioning of the staff in the hospital.
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To refer to complete question, see below:
During a discussion of concern about approaches used with aggressive patients in the Emergency Department, several staff members express concern for their safety. As a leader, the nurse manager should:
a. Look directly at speakers and acknowledge their comments.
b. Promise to implement each suggestion that is made.
c. Implement the idea that receives the most discussion.
d. Listen but implement the plan that she had in mind before the discussion began.
The drug development process involves many milestones. To be approved, potential drugs must demonstrate a positive patient outcome with minimization of harm. This is called ________.
To be approved, potential drugs must demonstrate a positive patient outcome with minimization of harm. This process of examine is simply called Clinical trials.
Recently, significant public investments in health care to find the medical treatments with the highest value have been sparked by the increase in health care expenses in the United States. The American Recovery and Reinvestment Act of 2009 specifically allocated $1.1 billion for "comparative effectiveness" research to assess "...clinical outcomes, effectiveness, and appropriateness of items, services, and procedures that are used to prevent, diagnose, or treat diseases, disorders, and other health conditions." 1 Despite the fact that a variety of study designs can achieve these objectives, randomized controlled trials (RCTs), in particular, continue to serve as the gold standard for comparing disease therapies. Clinical trial execution, however, requires a meticulous strategy based on scientific, statistical, moral, and legal considerations.
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the home health nurse is developing a treatment care plan for an elderly retired client with Medicare insurance. What factor will the nurse take into
The home health nurse is developing a treatment care plan for an elderly retired client with Medicare insurance. The nurse will under take the factor that the treatments are often covered by publicly financed health care plans if the practitioner orders them.
Initiated in 1965 by the Social Security Administration and currently run by the Centers for Medicare and Medicaid Services, Medicare is a government-sponsored universal health insurance programme in the United States.
In most cases, you only need to register for Parts A and B once. You have a choice every year regarding how you obtain health insurance (and add or switch drug coverage). Medicare is distinct from private insurance because it doesn't provide couples' or family plans.
As determined by Money Geek's scoring methodology, the best Medicare Advantage plans are Blue Cross Blue Shield for preferred provider organisations and United Healthcare for health maintenance organisations.
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A nurse working in a community health center is preparing a flow sheet detailing essential screenings according to age group. At which developmental stage on the chart should the nurse add scoliosis screening
The nurse should add scoliosis screening in the Pre-adolescent/adolescent phase of the developmental stage.
Scoliosis screening refers to physical testing of the body which includes full body X ray, spinal radiograph and MRI. It is performed in growing children because at that age they tend to grow stronger bones and muscles. The major symptoms of Scoliosis is uneven shoulders, uneven length of the arms of legs etc. It is caused due to degeneration of spinal disc and is irreversible in nature and so far not much cure has been determined. Adolescent idiopathic scoliosis is the most common type of scoliosis and is usually diagnosed during age of puberty.
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A woman birth her infant 24 hours ago by cesarean. Which assessment findings should be reported to the assigned nurse
The assessment findings that should be reported to the assigned nurse are:
Uterus feels boggyThe client reports breakthrough pain level of 7-8The client may face a variety of discomforts and issues following a caesarean section delivery. The fundal height is normal in this case, the volume of blood is normal, and minor abdominal distention with hypoactive bowel sound is predicted. The swampy uterus and elevated pain level are significant observations that should be mentioned to the RN. A swollen uterus might cause bleeding, and pain levels of 7-8 must be treated with prescribed opiates.
Caesarean section, often known as C-section or caesarean birth, is a surgical technique in which one or more infants are born through an incision in the mother's belly, which is frequently used because vaginal delivery might endanger the baby or mother.
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Medical science has developed several medications to help men who suffer from erectile difficulties. Which of these is NOT one of these medications
Medical science has developed several medications to help men with erectile difficulties. the following is NOT one of these medicines metamizole sodium.
What is erectile dysfunction?Erectile dysfunction, also known as impotence, occurs when a man cannot get or maintain an erection sufficient. This condition is fairly common in men. The risk of impotence may increase with age.
The most common symptom of erectile dysfunction is difficulty getting an erection and difficulty maintaining an erection during sexual activity. In addition, someone who has impotence also does not have an erection in the morning. If you experience this, immediately consult a doctor.
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Medical science has developed several medications to help men who suffer from erectile difficulties. Which of these is NOT one of these medications
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A patient presents with malaise, a fever, and joint pain. If a systemic lupus erythematosus (SLE) diagnosis is being considered, which additional assessments should the nurse perform
If a systemic lupus erythematosus (SLE) diagnosis is being evaluated, the nurse should do the following tests:
Take patient blood pressureEnsure that urine is collected for a urinalysisAsk the patient simple questions and note patient responseThe most prevalent symptoms in new instances or recurring active SLE flares are fatigue, fever, arthralgia, or weight abnormalities. Fatigue, the most prevalent constitutional symptom of SLE, might be caused by active SLE, drugs, lifestyle behaviours, or coexisting fibromyalgia or mental disorders. Children with SLE frequently have cardiovascular signs including such hypertension, pericarditis, or blood dyscrasias. An examination that the nurse may take to assist detect SLE is taking a patient's blood pressure.
Proteinuria, hematuria, as well as nephritis are common urinary symptoms in children with SLE. The nurse can undertake an examination to help detect SLE by collecting a urine sample for just a urinalysis. In children with SLE, neurologic symptoms such as headaches, mood problems, cognitive difficulties, and seizure disorders are common. Simple inquiries about the patient's projected developmental age can assist assess basic brain abilities and it may help diagnose SLE.
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As part of your health promotion education for a new patient, you explain that the risk factors for skin cancer include:
Answer:
use search engine and you'll find your answers
As part of your health promotion education for a new patient, you explain that the risk factors for skin cancer include:
1. Exposure to Ultraviolet (UV) Radiation: Prolonged exposure to UV radiation from the sun or artificial sources, such as tanning beds, increases the risk of developing skin cancer. Unprotected and excessive sun exposure over time can damage the DNA in skin cells, leading to mutations and the development of cancerous cells.
2. Fair Skin and Light Eye/Hair Color: People with fair skin, light-colored eyes (such as blue or green), and light-colored hair (such as blonde or red) have less melanin, the pigment that provides some protection against UV radiation. As a result, they are more susceptible to the harmful effects of UV radiation and have a higher risk of developing skin cancer.
3. History of Sunburns: Experiencing multiple severe sunburns, especially during childhood or adolescence, increases the risk of developing skin cancer later in life. Sunburns indicate overexposure to UV radiation, which can lead to DNA damage and an increased likelihood of cancer formation.
4. Family History: Having a family history of skin cancer, particularly melanoma, increases the risk of developing the disease. Genetic factors can contribute to a person's susceptibility to skin cancer, so it is important to be aware of any family history of the disease.
5. Personal History of Skin Cancer: Individuals who have previously been diagnosed with skin cancer have an increased risk of developing new skin cancers. It is important for individuals with a history of skin cancer to have regular check-ups and follow-up appointments to monitor for any new or recurring lesions.
6. Weakened Immune System: A weakened immune system, such as in individuals with organ transplants, certain autoimmune conditions, or HIV/AIDS, can increase the risk of developing skin cancer. A properly functioning immune system helps detect and eliminate cancerous cells, so a weakened immune response can allow cancer to develop more easily.
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rational harm-benefit assessments by age group are required for continued covid-19 vaccination
Follow-up covid-19 vaccination is needed, but with a hazard-benefit analysis based on age groups because some ages have a history of certain diseases.
What is covid?Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus.
Most people who contract COVID-19 will experience mild to moderate symptoms and will recover without special treatment. However, some people will become seriously ill and need medical assistance.
To reduce the risk of transmission, vaccination is carried out which will make antibodies to learn and recognize the attenuated virus. So the body will be exposed to the virus and reduce the risk of exposure.
In carrying out follow-up vaccinations, analysis is needed for several age groups because certain ages have a history of certain diseases.
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A client who is experiencing an acute attack of gouty arthritis is prescribed Colchicine USP 1 mg PO daily. Which information is most important for the nurse to provide the client
The nurse should provide the information about the side effects of Colchicine USP. Only when the medication is required to stop a current episode do patients take substantial doses of colchicine over a short period of time (a few hours). Don't use colchicine much because it may cause weakness and many diseases.
Anti-inflammatory painkillers are the most frequently recommended treatment for a gout attack, although not everyone can take these medications. Gout attacks can be treated alternatively with colchicine for patients who cannot take anti-inflammatory medicines. Colchicine reduces the quantity of white blood cells that enter inflammatory areas, which is how it works. Colchicine lessens gout attack swelling and discomfort while assisting in breaking the cycle of inflammation.Gout produces flare-ups of excruciating joint inflammation in one or more joints. It is brought on by an accumulation of uric acid, a naturally occurring substance in your blood (urate). The amount of uric acid in your blood may occasionally increase to the point where microscopic grit-like crystals form.
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A nurse is teaching a new guardian how to correctly use a car seat. Which of the following statements by the guardian indicates an understanding of the teaching
The understanding shown by the new guardian about using a car seat for babies properly is "I should keep my baby in a rear-facing car seat until he is 2 years old."
A baby car seat is a car seat specifically designed for babies or children of a certain age to protect them while in the car. This chair is specifically designed to maintain safety when traveling with children.
Baby car seats are shaped like baskets, usually used for newborns up to a maximum weight of 10 kilograms. The position is facing backward and please pay attention, every baby weighing under 10 kilograms, not even one-year-old must always face the back. Because it is safer for the bones that are not yet strong, especially if the car has to brake suddenly.
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which medication is beneficial for reducing presurgery anxiety and decreasing the patient's ability to remmber an uncomfortable medical procedure
Midazolam is the medication that can reduce the pre-surgery anxiety and decrease the patient's ability to remember an uncomfortable medical procedure.
Midazolam is a medicine that can induce amnesia and therefore temporarily reduced the memory of the patient. It also produced the effect of sleepiness or drowsiness. It belongs to the class of benzodiazepines that are known to slow down the brain activity.
Anxiety is the response of the body when under stress. It causes shivering, palpitations, fastening of heart rate and also tiredness. A person feels uneasy during anxiety. Anxiety is normal during stress conditions but may be problematic when person suffers anxiety even in normal situations.
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What is a warning sign that suggests a weight-loss plan is a fad diet rather than a healthy weight-loss plan
The warning sign that suggests a weight-loss plan is a fad diet rather than a healthy weight-loss plan are promising rapid weight loss, requires eliminating foods, has rigid rules and severely restrict calories.
A fad diet is a diet that is popular for a brief period of time, analogous to fashion fads, without being a normal dietary prescription and frequently making pseudoscientific or unrealistic claims for rapid weight reduction or health advantages. Fad diets are not backed up by clinical research, and their health advice are not peer-reviewed, therefore they frequently make unfounded claims concerning health and illness.
A healthy diet is one that promotes or maintains good health. A healthy diet supplies the body with vital nourishment, including liquids, macronutrients like protein, micronutrients like vitamins, and enough fibre and dietary energy. A healthy diet may include fruits, vegetables, and whole grains, as well as little or no processed food or sugary beverages. A mix of plant-based and animal-based foods can meet the needs for a balanced diet, however vegans will need a non-plant source of vitamin B12.
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30. When applying towels around the incision a. It is important that the skin be dry b. Drape the area nearest you first c. Walk to the opposite side of the patient to place the last towel d. All of the above
When applying towels around the incision option d. All of the above is correct, as it it is important to have dry skin, nearest area is to be draped first and last towel should be placed on opposite side.
An incision is a cut through the skin that's made during surgery. It's also called a surgical crack. Some lacerations are small, others are long. The size of the gash depends on the kind of surgery you had.
Dry skin accompanies most surgical procedures as a result of the temporary towel swelling that takes place with any operation. This temporary stretch causes the skin to produce have further of the external skin than it needs and once the lump resolves, this skin sloughs off.
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The nurse is educating parents of a child admitted to the hospital with rubella (German measles). Which statement by the parents indicates the further education is needed
The statement "Antibiotics are needed to help our child recover from rubella." by the parents indicates the further education is needed.
This statement shows that the parents are not aware of the serious complications that rubella can cause, such as encephalitis and congenital rubella syndrome (CRS) which can lead to birth defects in an unborn baby if the mother contracts rubella during pregnancy. Therefore, the nurse should provide more education on the potential complications of rubella and the importance of preventing the spread of the disease.
Another example would be if the parents say "We can't give our child the rubella vaccine because it causes autism" this statement also shows a lack of understanding about the facts and myths about vaccination and the importance of vaccination in preventing the spread of the disease.
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The treatment of CNS cancers and infections is hampered by the inability of most drugs to cross the BBB. What would be the dangers of altering the BBB so that drugs could more easily enter the CNS
The major danger of altering the BBB so that drugs could more easily enter the CNS is that composition of the CSF would change and more closely resemble plasma, and bacteria and viruses might more easily enter the CNS.
CNS refers to Central Nervous System, while BBB refers to blood-brain barrier. The drugs are incompetent to cross the BBB because they lack the protein binding capacity or lipid insolubility. Changing this condition through manual means can change the final composition of nervous system and it may become susceptible to other infections which can further pose damage to health, hence it must be avoided in many circumstances. However once drugs cross through the BBB, there is instantaneous equilibration of drug throughout the entire brain volume.
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