how enzymes inhibitions studies in the formulation and development of drugs​

Answers

Answer 1

Answer:

Enzyme inhibitors may alter the elimination rate of a particular drug or inhibit detoxication pathways

Explanation:

An enzyme inhibitor is a chemical compound capable of binding to an enzyme in order to reduce its activity. An enzyme inhibitor may bind to an active site and thus decreases the rate of reaction (direct inhibition). Enzyme inhibitors may act 1-to Inhibit detoxification enzymes and 2-reduce the elimination rate of enzyme drugs, thereby having dose-dependent toxicity effects. For example, many medicines are based on the inhibition of Cytochromes P450 (CYPs) proteins, which are a superfamily of enzymes required for drug metabolism.


Related Questions

If Darwin was to be alive today, what do you think will be his observation on evolution?​

Answers

Darwin would be happy that his theory of evolution is correct. Stating that biological evolution is through natural selection of inherited traits that enable a species to survive, compete and reproduce.

Role of Ibn Sina in the field of medicine?

Answers

Answer:

Although Avicenna made advances in pharmacology and in clinical practice, his greatest contribution was probably in the philosophy of medicine. He created a system of medicine that today we would call “holistic” and in which physical and psychological factors, drugs, and diet were combined in treating patients.

Explanation:

I hope I helped

Answer:

Although Avicenna made advances in pharmacology and in clinical practice, his greatest contribution was probably in the philosophy of medicine. He created a system of medicine that today we would call “holistic” and in which physical and psychological factors, drugs, and diet were combined in treating patients.

Explanation:

Hope it helped

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Describe how natural selection is related to evolution

Answers

Answer:

The mechanism that Darwin proposed for evolution is natural selection. Because resources are limited in nature, organisms with heritable traits that favor survival and reproduction will tend to leave more offspring than their peers, causing the traits to increase in frequency over generations.

Explanation:

A ______ is an injury that puts pressure on the brain.

A) meningitis
B) myeloma
C) subdural hematoma
D) carcinoma

Answers

It is subdural hematoma

A subdural hematoma is a collection of blood outside the brain. They're usually caused by serious head injuries. Bleeding and added pressure on the brain from a subdural hematoma can be life-threatening.

If a colorblind female (XnXn) and a normal male (XNY) have a son, what are the chances he would be colorblind?

0%
100%
50%
25%

Answers

Answer:

50%

Explanation:

Make a punnet square

     Xn  Xn

XN XNXn XNXn

Y   XnY XnY

Colorblind is a recessive trait (n) so the fraction is 2/4

If a colorblind female (XnXn) and a normal male (XNY) have a son, then the chances he would be colorblind is 50%.

Inheritance linked to the X chromosome is different from the inheritance of autonomic chromosomes because males inherit only one X chromosome.

Conversely, females inherit two X chromosomes, thereby resembling mendelian autonomic inheritance.

In the Punnet square:

          Xn           Xn

XN   XNXn        XNXn

Y       XnY           XnY

In conclusion, if a colorblind female (XnXn) and a normal male (XNY) have a son, then the chances he would be colorblind is 50%.

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Which of these options is a good hypothesis? A. if i increase the amount of baking soda my cookies will be taller B. Check out this cool volcano! C. Most people prefer vanilla ice cream

Answers

Answer:

A. because its assuming what will happen

Answer:

A

Explanation:

It says if I

how do stars recycle matter?

Answers

Answer:

Stars forge heavy elements and return their gas to space. This material enriches gas clouds from which new stars are formed, and the cycle continues. Each generation of stars is made in part from the ashes of previous generations. The material of stars is recycled over billions of years.

Explanation:

The material of stars is recycled over billions of years. Interstellar gas clouds collapse to make stars. Stars forge heavy elements and return their gas to space. This material enriches gas clouds from which new stars are formed, and the cycle continues. Each generation of stars is made in part from the ashes of previous generations.

Hope this helps

Hope this is right

Answer:

Stars forge heavy elements and return their gas to space. This material enriches gas clouds from which new stars are formed, and the cycle continues. Each generation of stars is made in part from the ashes of previous generations. The material of stars is recycled over billions of years.

Furthermore, Rubin and colleagues find evidence that this new fuel could come in the form of recycled gas once ejected by the galaxy, pushed out by massive supernovae events or by the light pressure of massive newborn stars, but which does not leave the gravitational clutches of the galaxy completely.

can some one help me

Answers

Answer:

to tell the truth i do not understand no ways it would be a long text if i tell u the answer

Which three events that affect Earth's crust happen very quickly?
A. Earthquakes
B. Folding
C. Fault formation
D. Volcanic eruptions

Answers

Answer:

Earthquakes,volcanic eruptions and i think fault formation sorry if this is incorrect but i'm pretty sure this is correct.

Explanation:

[40 POINTS!!!!]
According to the National Institute of Health, atrial fibrillation (A-F) occurs if rapid, disorganized electrical signals causing the heart's two upper chambers, called the atria, to fibrillate. The term "fibrillate" means to contract very fast and irregularly. In A-F, blood pools in the atria. It isn't pumped completely into the heart's two lower chambers, called the ventricles. As a result, the heart's upper and lower chambers don't work together as they should. Based on the passage above, how will atrial fibrillation affect blood pressure?
A. It will lower blood pressure because less blood is pumped per beat.
B. It will increase blood pressure because the heart is contracting faster.
C. It will increase blood pressure because the atria fill fully with blood.
D. It will lower blood pressure because blood volume drops in the atria.

Answers

The answer is B. It will increase blood pressure because the heart is contracting faster

Answer:

A. It will lower blood pressure because less blood is pumped per beat.

Explanation:

I thought B might be a potential answer, but since the atria are not filling properly and heart rate is increased, it would make sense that blood pressure drops (effect of faster heart contraction is negated by the drop in blood volume in the atria).

Use the information below to answer the following question.
Biofeedback consists of conscious efforts to control body responses that are
usually involuntary
The part of the brain in which conscious efforts to control body responses
through biofeedback originate is the
Select one:
O A. medulla
O B. cerebellum
O C. cerebrum
OD. hypothalamus

Answers

D. I think that should be the answer

What is the difference between a codon and an anticodon?

Answers

Answer: A codon is the triplet sequence in the messenger RNA (mRNA) transcript which specifies a corresponding amino acid (or a start or stop command). An anticodon is the corresponding triplet sequence on the transfer RNA (tRNA) which brings in the specific amino acid to the ribosome during translation.

______ tissue moves the body and its parts.

Answers

Answer:

Musle Tissue

Explanation:

Muscle tissue helps in body & its parts movements. It is able to do so, as it consists of special contractile cells - which can contract (shorten) in response to stimulus. And, then help the movable bones to move.

14. Why
are sea urchins so important in the estuary? What would happen if they were to die off?

Answers

Their predators with them as their main source of energy would die off. Algae, kelp, and many more would over grow and overpopulate estuaries.

is 8 1/5 greater than 2 1/10

Answers

Answer:

8 1/5 > 2 1/10 = True

Explanation:

Answer:

No

Explanation:

8 1/5 is equal to 41/5 which is equal 20.5/10 while

2 1/10 equals 21/10

The haploid number is 60, so that means the diploid number is *

A) 60

B) 120

C) 30

D) 15

PLEASE HELP

Answers

Answer:

option B- 120

Explanation:

haploid(n) means a complete set of chromosomes, haploids have half number of chromosomes of a diploid(2n) organism. while diploid means two complete set of chromosomes.

Describe the genetic differences and similarities from the start of Meiosis to the
end of meiosis.

Answers

Meiosis I begins with one diploid parent cell and ends with two haploid daughter cells, halving the number of chromosomes in each cell. Meiosis II starts with two haploid parent cells and ends with four haploid daughter cells, maintaining the number of chromosomes in each cell.

Oxygen is carried through the blood by the protein hemoglobin. It is said in the article that a mutation of this protein known as
is the result of oxygen poor blood, which appears blue in veins.
A)Hemotosin
B)Methemeglobin
C)Hemolethoglobin
D)Blood Platelets

Answers

Answer:

The correct answer is - B) Methemeglobin.

Explanation:

Methemeglobin is a blood disorder due to the mutation in the hemoglobin which is known as the result of oxygen-less blood. In this disorder, the tissue did not get enough oxygen and appeared to be purple, or blue.

In this mutated form of hemoglobin iron atoms present in ferric instead of the ferrous state and therefore not able to bind with oxygen. It appears blue in veins and tissues look blue or purple.

P2: How do genes determine an individual's traits? (click here to learn how to correctly check the box) Correctly choose one: Genes directly lead to traits. I Genes are random and don't lead to traits. Genes give organisms the ability to change their traits Genes are instructions for making protein molecules and protein molecules determine traits.​

Answers

Answer:

genes are the basic sequence of DNA that controls the traits of an organisms.

Explanation:

genes have nucleotide sequences. these sequences are involved in transmission of characters from one generation to other. if their is an error occur in this sequence the new offspring will b dissimilar from parent in this secific character which chnaged.

central dogma is the basic process through which genes are controlling the traits. first step is transcriotion through which DNA or gene is transcribed into mRNA sequence. then the second step is translation in which mRNA is translated into protein. in this way by making proteins genes control the traits or functiong of a body.

Why is absolute dating more accurate than relative dating?

Answers

Answer:

Absolute dating is a technique that uses radioactive minerals present in rocks and fossils while relative dating compare the sample in terms of age difference. However, absolute dating is more accurate because it uses half-life of an element and provides dates in years.

-) Use the drop-down menus to classify each worm into the appropriate group. planarians marine worms leeches pinworms tapeworms. .........

Answers

Answer:

planarians =  flatworms

marine worms= segmented worms

leeches= segmented worms

pinworms= roundworms

tapeworms=  flatworms

Explanation:

I took it on edge lol

Answer:

yup right

Explanation:

98. Which of the following substances requires a transmembrane protein in order to cross a cell membrane?

a.
water

b.
glucose

c.
sodium ions

d.
All of the above are correct.
100. Which of the following vesicles contain lytic enzymes:

a.
central vacuole

b.
peroxisomes

c.
lysosomes

d.
transport vesicle

101. You look at cells under a microscope. You see cell walls and membrane bound organelles. You conclude that the cells are:

a.
animal cells

b.
archaea cells

c.
plant cells

d.
bacterial cells

Answers

Answer:

la le rechaza ace chuchu la lechuza la ase zhu ala aa anldbduevvla lechuaza

Which number label represents the cell membrane?
1
2
4
6

Answers

The cell membrane is near to the cell wall, it surrounds the cell so it will be 1

1. The framework of a human body that provides structure and allowing movement.
A. Skeletal System
B. Muscular System
C. Integumentary System
D. Digestive System​

Answers

the answer is A. skeletal system

Answer:

a skeletal system

hope it helps :-) :-)

Monitoring a population's age structure plays an important role in successful wildlife management. Which of the following scenarios can be an indicator of overexploitation in fish?
A)
fish catch not reaching older ages
B)
decline in fish catch
C)
both a and b
D)
none of the above

Answers

Answer:

A i already search that

Explanation:

i dont need explanation

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The Rock-Soil Cycle was first researched?​

Answers

First proposed by James Hutton in the 18th century

Can any earth life thrive in open outer space?

Answers

No, because there is no oxygen.

Which of the following is NOT a base found in RNA?
O Cytosine
O Uracil
O Adenine
O Thymine

Answers

Answer:

Thymine

Explanation:

Only one not found in RNA

DNA carries the information needed to make proteins. How is this information used to make
proteins?

Answers

Answer:

There is a protein synthesis cycle

Explanation:

The whole cycle goes through Transcription and Translation

where the DNA gets converted into RNA

Answer: DNA is transcribed into mRNA. Ribosomes "read" the mRNA and translate each group of three nucleotides into amino acids to build proteins, with the help of tRNA.

What natural mechanism the body uses to maintain homeostasis give 2 examples

Answers

Answer:

1,food

2,movement

Explanation:

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